Implications of the HP Discovery
Acute pancreatitis starts with trypsin activation within the pancreatic acinar cells - not from digestive enzymes leaking from injured pancreatic ducts!
Chronic pancreatitis develops from multiple attacks of acute pancreatitis - not from duct obstruction by calcium.
Pancreatic Cancer - occurs from chronic inflammation of the pancreas - not from an oncogene
Therapy should be directed at preventing excessive, premature trypsin activation.